Symbol
Name
ID

Cebpb
CCAAT/enhancer binding protein beta
MGI:88373

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

abnormal osteoclast differentiation

impaired macrophage phagocytosis

enlarged spleen

decreased osteoclast cell number

abnormal plasma cell morphology

abnormal osteoclast morphology

abnormal spleen red pulp morphology

abnormal spleen white pulp morphology

abnormal spleen secondary B follicle morphology

increased IgG level

abnormal T-helper 1 physiology

abnormal T-helper 2 physiology

abnormal macrophage physiology

abnormal osteoclast physiology

decreased circulating interleukin-10 level

decreased circulating interleukin-12 level

increased circulating interleukin-6 level

increased circulating tumor necrosis factor level

abnormal tumor necrosis factor level

enlarged mesenteric lymph nodes

abnormal lymph node cortex morphology

abnormal lymph node B cell domain morphology

abnormal lymph node secondary follicle morphology

abnormal lymph node T cell domain morphology

abnormal lymph node medulla morphology

abnormal lymph node medullary cord morphology

enlarged lymph nodes

enlarged axillary lymph nodes

enlarged inguinal lymph nodes

enlarged submandibular lymph nodes

abnormal mucosa-associated lymphoid tissue morphology

decreased susceptibility to type IV hypersensitivity reaction

abnormal cell-mediated immunity

abnormal humoral immune response

increased interleukin-12 secretion

decreased susceptibility to endotoxin shock

granulomatous inflammation

myositis

glomerulonephritis

abnormal innate immunity

decreased susceptibility to bacterial infection

decreased susceptibility to bacterial infection induced morbidity/mortality

increased susceptibility to bacterial infection

increased susceptibility to fungal infection

Availability

Mouse Genotype

Cebpb^tm1.1Acle/Cebpb^tm1.1Acle

Cebpb^tm1Aki/Cebpb^tm1Aki

Cebpb^tm1Kish/Cebpb^tm1Kish

Cebpb^tm1Pfj/Cebpb^tm1Pfj

Cebpb^tm1Vpo/Cebpb^tm1Vpo

Cebpb^tm2.1Acle/Cebpb^tm2.1Acle

Cebpb^tm3Nerl/Cebpb^tm3Nerl

Cebpb^tm1.1Elgaz/Cebpb^tm1.1Elgaz
Lyz2^{em1.1(cre)Elgaz}/Lyz2⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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